GDAP1L1 antibody (Middle Region)

Catalog No. ABIN5516769

Product Details anti-GDAP1L1 Antibody

Target: GDAP1L1 (Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDAP1L1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELWLCGCAFT LADVLLGATL HRLKFLGLSK KYWEDGSRPN LQSFFERVQR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GDAP1L1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GDAP1L1

Target: GDAP1L1 (Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1))

Alternative Name: GDAP1L1 (GDAP1L1 Products)

Synonyms: GDAP1L1 antibody, MGC146673 antibody, dJ881L22.1 antibody, dJ995J12.1.1 antibody, Gdap1l antibody, ganglioside induced differentiation associated protein 1 like 1 antibody, ganglioside induced differentiation associated protein 1-like 1 antibody, ganglioside-induced differentiation-associated protein 1-like 1 antibody, GDAP1L1 antibody, gdap1l1 antibody, Gdap1l1 antibody

Background: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.

Alias Symbols: dJ881L22.1, dJ995J12.1.1

Protein Size: 557

Gene ID: 78997

NCBI Accession: NM_001256737, NP_001243666

UniProt: Q96MZ0