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SPARC antibody (Middle Region)
SPARC
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SPARC Antibody
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Target
See all SPARC Antibodies
SPARC
(Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
Binding Specificity
All epitopes for SPARC antibodies
Middle Region
Reactivity
All reactivities for SPARC antibodies
Human
Host
All hosts for SPARC antibodies
Rabbit
Clonality
All clonalities for SPARC antibodies
Polyclonal
Conjugate
All conjugates for SPARC antibodies
This SPARC antibody is un-conjugated
Application
All applications for SPARC antibodies
Western Blotting (WB)
Sequence
YIPPCLDSEL TEFPLRMRDW LKNVLVTLYE RDEDNNLLTE KQKLRVKKIH
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SPARC
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SPARC
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Target
SPARC
(Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
Alternative Name
SPARC (SPARC Products )
Synonyms
ON antibody, AA517111 antibody, BM-40 antibody, hm:zeh0062 antibody, SPARC antibody, sparc antibody, secreted protein acidic and cysteine rich antibody, secreted acidic cysteine rich glycoprotein antibody, secreted protein, acidic, cysteine-rich (osteonectin) antibody, secreted protein, acidic, cysteine-rich (osteonectin) L homeolog antibody, secreted protein, acidic, cysteine-rich (osteonectin) S homeolog antibody, SPARC antibody, Sparc antibody, sparc antibody, sparc.L antibody, sparc.S antibody
Background
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. Alias Symbols: ON, BM-40 Protein Size: 167
Gene ID
6678
NCBI Accession
NM_001309443 , NP_003109
UniProt
P09486
Pathways
Autophagy
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