HRPT2 antibody (Middle Region)
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- Target See all HRPT2 (CDC73) Antibodies
- HRPT2 (CDC73) (Parafibromin (CDC73))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HRPT2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LKSVTEGASA RKTQTPAAQP VPRPVSQARP PPNQKKGSRT PIIIIPAATT
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CDC73
- Top Product
- Discover our top product CDC73 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HRPT2 (CDC73) (Parafibromin (CDC73))
- Alternative Name
- CDC73 (CDC73 Products)
- Synonyms
- C1orf28 antibody, HPTJT antibody, HRPT2 antibody, HYX antibody, 8430414L16Rik antibody, BC027756 antibody, C130030P16Rik antibody, C81219 antibody, Hrpt2 antibody, hrpt2 antibody, zgc:63956 antibody, MGC108428 antibody, cdc73 antibody, LOC100222932 antibody, cell division cycle 73 antibody, cell division cycle 73, Paf1/RNA polymerase II complex component antibody, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antibody, parafibromin antibody, cell division cycle 73 S homeolog antibody, CDC73 antibody, Cdc73 antibody, cdc73 antibody, Tsp_03925 antibody, Tsp_04052 antibody, Tsp_04125 antibody, cdc73.S antibody
- Background
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This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Alias Symbols: HYX, FIHP, HPTJT, HRPT1, HRPT2, C1orf28
Protein Size: 531 - Gene ID
- 79577
- NCBI Accession
- NM_024529, NP_078805
- UniProt
- Q6P1J9
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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