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GLCE antibody (Middle Region)
GLCE
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GLCE Antibody
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Target
See all GLCE Antibodies
GLCE
(Glucuronic Acid Epimerase (GLCE))
Binding Specificity
All epitopes for GLCE antibodies
Middle Region
Reactivity
All reactivities for GLCE antibodies
Human
Host
All hosts for GLCE antibodies
Rabbit
Clonality
All clonalities for GLCE antibodies
Polyclonal
Conjugate
All conjugates for GLCE antibodies
This GLCE antibody is un-conjugated
Application
All applications for GLCE antibodies
Western Blotting (WB)
Sequence
TKDHIFLNSA LRATAPYKFL SEQHGVKAVF MNKHDWYEEY PTTPSSFVLN
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human GLCE
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for GLCE
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Target
GLCE
(Glucuronic Acid Epimerase (GLCE))
Alternative Name
GLCE (GLCE Products )
Synonyms
HSEPI antibody, RGD1565253 antibody, MGC79110 antibody, 1110017N23Rik antibody, AI747411 antibody, C130034A12Rik antibody, Hsepi antibody, glce antibody, glcel antibody, sb:eu394 antibody, zgc:136701 antibody, glucuronic acid epimerase antibody, glucuronic acid epimerase L homeolog antibody, glucuronyl C5-epimerase antibody, glucuronic acid epimerase b antibody, glucuronic acid epimerase a antibody, GLCE antibody, Glce antibody, glce.L antibody, glce antibody, glceb antibody, glcea antibody
Background
Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM, Jun 2008] Alias Symbols: HSEPI Protein Size: 617
Gene ID
26035
NCBI Accession
NM_015554 , NP_056369
UniProt
O94923
Pathways
Glycosaminoglycan Metabolic Process
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