PAR-3 antibody, PAR3 antibody, par3 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, F730031A08 antibody, f2 antibody, f2rl2 antibody, coagulation factor II thrombin receptor like 2 antibody, coagulation factor II (thrombin) receptor-like 2 antibody, coagulation factor II antibody, coagulation factor II, thrombin antibody, coagulation factor II, thrombin L homeolog antibody, coagulation factor II (thrombin) receptor-like 2 L homeolog antibody, F2RL2 antibody, f2rl2 antibody, F2 antibody, F2rl2 antibody, f2.L antibody, f2rl2.L antibody
Background
This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms.