IL3RA antibody (C-Term)

Catalog No. ABIN5517096

Product Details anti-IL3RA Antibody

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL3RA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CRRYLVMQRL FPRIPHMKDP IGDSFQNDKL VVWEAGKAGL EECLVTEVQV

Characteristics: This is a rabbit polyclonal antibody against IL3RA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL3RA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: IL3RA (IL3RA Products)

Synonyms: CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody

Background: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

Alias Symbols: IL3RA, IL3R,

Protein Interaction Partner: LNX1, FOXP1, SGK2, SAE1, NR0B2, GNA12, CDC25A, CDK1, PPP1CC, JAK1, IL3, CSF2RB, CSF2, CISH, JAK2,

Protein Size: 378

Gene ID: 3563

NCBI Accession: XP_005274837

UniProt: P26951

Pathways: JAK-STAT Signaling