SRSF10 antibody (Middle Region)

Catalog No. ABIN5517121

Product Details anti-SRSF10 Antibody

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SFDYNYRRSY SPRNSRPTGR PRRSRSHSDN DRFKHRNRSF SRSKSNSRSR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRSF10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRSF10

Target: SRSF10 (serine/arginine-Rich Splicing Factor 10 (SRSF10))

Alternative Name: SRSF10 (SRSF10 Products)

Synonyms: FUSIP1 antibody, SFRS13A antibody, FUSIP2 antibody, NSSR antibody, SFRS13 antibody, SRp38 antibody, SRrp40 antibody, TASR antibody, TASR1 antibody, TASR2 antibody, Fusip1 antibody, NSSR1 antibody, NSSR2 antibody, Nssr antibody, Sfrs13a antibody, Srsf13a antibody, fusip1 antibody, fusip2 antibody, nssr antibody, sfrs13 antibody, sfrs13a antibody, srp38 antibody, srrp40 antibody, tasr antibody, tasr1 antibody, tasr2 antibody, serine and arginine rich splicing factor 10 antibody, serine/arginine-rich splicing factor 10 antibody, serine/arginine-rich splicing factor 10 S homeolog antibody, SRSF10 antibody, Srsf10 antibody, srsf10.S antibody

Background: This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants.

Alias Symbols: NSSR, TASR, SRp38, TASR1, TASR2, FUSIP1, FUSIP2, SFRS13, SRrp40, SFRS13A, PPP1R149

Protein Size: 262

Gene ID: 10772

NCBI Accession: NM_001191005, NP_001177934

UniProt: O75494

Pathways: Ribonucleoprotein Complex Subunit Organization