MMP15 antibody (Middle Region)

Catalog No. ABIN5517170

Product Details anti-MMP15 Antibody

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP15 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DDLRGIQQLY GTPDGQPQPT QPLPTVTPRR PGRPDHRPPR PPQPPPPGGK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MMP15

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMP15

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Alternative Name: MMP15 (MMP15 Products)

Synonyms: AI503551 antibody, MT2-MMP antibody, MTMMP2 antibody, SMCP-2 antibody, matrix metallopeptidase 15 antibody, MMP15 antibody, Mmp15 antibody

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.

Alias Symbols: MTMMP2, SMCP-2, MT2-MMP

Protein Size: 669

Gene ID: 4324

NCBI Accession: NM_002428, NP_002419

UniProt: P51511