SNW1 antibody (C-Term)

Catalog No. ABIN5517224

Product Details anti-SNW1 Antibody

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNW1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SDRRQRGREG PVQFEEDPFG LDKFLEEAKQ HGGSKRPSDS SRPKEHEHEG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SNW1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNW1

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Alternative Name: SNW1 (SNW1 Products)

Synonyms: Gle1l1 antibody, Skiip antibody, bx42 antibody, ncoa-62 antibody, prp45 antibody, prpf45 antibody, skiip antibody, skip antibody, Bx42 antibody, NCOA-62 antibody, PRPF45 antibody, Prp45 antibody, SKIIP antibody, SKIP antibody, 2310008B08Rik antibody, AW048543 antibody, NCoA-62 antibody, SNW domain containing 1 antibody, nuclear protein SkiP antibody, puff-specific protein Bx42 antibody, putative nuclear protein SkiP antibody, GLE1 RNA export mediator homolog (yeast), pseudogene 1 antibody, SNW domain containing 1 S homeolog antibody, snw1 antibody, PVX_002605 antibody, LOC5564605 antibody, Smp_105860 antibody, UREG_03916 antibody, Gle1-ps1 antibody, snw1.S antibody, SNW1 antibody, Snw1 antibody

Background: This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.

Alias Symbols: Bx42, SKIP, Prp45, SKIIP, PRPF45, NCOA-62

Protein Size: 536

Gene ID: 22938

NCBI Accession: NM_012245, NP_036377

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway