TAF9B antibody (C-Term)

Catalog No. ABIN5517354

Product Details anti-TAF9B Antibody

Target: TAF9B (TAF9B RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 31kDa (TAF9B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF9B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TAVQNVLINP SMIGPKNILI TTNMVSSQNT ANEANPLKRK HEDDDDNDIM

Characteristics: This is a rabbit polyclonal antibody against TAF9B. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TAF9B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF9B

Target: TAF9B (TAF9B RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 31kDa (TAF9B))

Alternative Name: TAF9B (TAF9B Products)

Synonyms: BC066223 antibody, Taf9l antibody, Dn7 antibody, TAFII31 antibody, DN-7 antibody, DN7 antibody, TAF9L antibody, TAFII31L antibody, TFIID-31 antibody, TATA-box binding protein associated factor 9B antibody, TATA-box binding protein associated factor 9b antibody, Taf9b antibody, TAF9B antibody

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.

Alias Symbols: TAF9B, TAF9L,

Protein Interaction Partner: TAF6L, DRAP1, USP22, HIST3H3, TAF1L, TAF9B, TRRAP, TBP, TAF9, TAF7, TAF6, TAF5, TAF4, TAF1, KAT2A, APP, UBC, TRIM15, SS18L1, TAF13, TAF10, TP53, RUNX1T1,

Protein Size: 251

Gene ID: 51616

NCBI Accession: NP_057059

UniProt: Q9HBM6

Pathways: Negative Regulation of intrinsic apoptotic Signaling