UBE2A antibody (Middle Region)

Catalog No. ABIN5517372

Product Details anti-UBE2A Antibody

Target: UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NVYADGSICL DILQNRWSPT YDVSSILTSI QSLLDEPNPN SPANSQAAQL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBE2A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBE2A

Target: UBE2A (ube2a) (Ubiquitin-Conjugating Enzyme E2A (ube2a))

Alternative Name: UBE2A (ube2a Products)

Synonyms: BHR6A antibody, HR6A antibody, hhr6a antibody, rad6a antibody, ubc2 antibody, mp:zf637-2-000771 antibody, si:bz46j2.4 antibody, wu:fa01h11 antibody, HHR6A antibody, MRXS30 antibody, MRXSN antibody, RAD6A antibody, UBC2 antibody, Mhr6a antibody, ubiquitin conjugating enzyme E2 A antibody, ubiquitin conjugating enzyme E2 A L homeolog antibody, ubiquitin-conjugating enzyme E2A (RAD6 homolog) antibody, ubiquitin-conjugating enzyme E2A antibody, UBE2A antibody, ube2a.L antibody, ube2a antibody, Ube2a antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.

Alias Symbols: UBC2, HHR6A, MRXSN, RAD6A, MRXS30

Protein Size: 152

Gene ID: 7319

NCBI Accession: NM_001282161, NP_001269090

UniProt: P49459