PHKA1 antibody (C-Term)

Catalog No. ABIN5517390

Product Details anti-PHKA1 Antibody

Target: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHKA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KQSPGTSMTP SSGSFPSAYD QQSSKDSRQG QWQRRRRLDG ALNRVPVGFY

Characteristics: This is a rabbit polyclonal antibody against KPB1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-PHKA1 antibody is: synthetic peptide directed towards the C-terminal of Human KPB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHKA1

Target: PHKA1 (phosphorylase Kinase, alpha 1 (Muscle) (PHKA1))

Alternative Name: PHKA1 (PHKA1 Products)

Synonyms: PHKA1 antibody, wu:fl37h01 antibody, 5330411D17 antibody, 9830108K24Rik antibody, Phka antibody, Pcyt1b antibody, PHKA antibody, phosphorylase kinase regulatory subunit alpha 1 antibody, phosphorylase kinase, alpha 1a (muscle) antibody, phosphorylase kinase, alpha 1 (muscle) antibody, phosphorylase kinase alpha 1 antibody, PHKA1 antibody, phka1a antibody, phka1 antibody, Phka1 antibody

Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.

Alias Symbols: PHKA

Protein Size: 1151

Gene ID: 5255

Pathways: Cellular Glucan Metabolic Process