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GLYR1 antibody (N-Term)
GLYR1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GLYR1 Antibody
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Target
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GLYR1
(Glyoxylate Reductase 1 Homolog (GLYR1))
Binding Specificity
All epitopes for GLYR1 antibodies
N-Term
Reactivity
All reactivities for GLYR1 antibodies
Human
Host
All hosts for GLYR1 antibodies
Rabbit
Clonality
All clonalities for GLYR1 antibodies
Polyclonal
Conjugate
All conjugates for GLYR1 antibodies
This GLYR1 antibody is un-conjugated
Application
All applications for GLYR1 antibodies
Western Blotting (WB)
Sequence
SSHNSSDDKN RRNSSEERSR PNSGDEKRKL SLSEGKVKKN MGEGKKRVSS
Characteristics
This is a rabbit polyclonal antibody against GLYR1. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLYR1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for GLYR1
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Target
GLYR1
(Glyoxylate Reductase 1 Homolog (GLYR1))
Alternative Name
GLYR1 (GLYR1 Products )
Synonyms
N-PAC antibody, BM045 antibody, HIBDL antibody, NP60 antibody, 2810419J22Rik antibody, 3930401K13Rik antibody, AW545332 antibody, Npac antibody, 3930401k13rik antibody, N-pac antibody, RGD1309459 antibody, glyoxylate reductase 1 homolog antibody, glyoxylate reductase 1 homolog (Arabidopsis) antibody, GLYR1 antibody, Glyr1 antibody
Background
GLYR1 may have oxidoreductase activity. It regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. It indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. It is recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). Alias Symbols: GLYR1, HIBDL, NP60, Protein Interaction Partner: C6orf165, EIF1AD, UBC, FHL2, CCNC, SUMO2, SUMO1, SUZ12, EED, RNF2, WHSC1L1, KDM1A, GEMIN4, ESR1, DHX9, SIRT7, ELAVL1, Protein Size: 484
Gene ID
84656
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