PJA1 antibody (Middle Region)

Catalog No. ABIN5517684

Product Details anti-PJA1 Antibody

Target: PJA1 (Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PJA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SEGDNDSGHE LMQPGVFMLD GNNNLEDDSS VSEDLEVDWS LFDGFADGLG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PJA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PJA1

Target: PJA1 (Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))

Alternative Name: PJA1 (PJA1 Products)

Synonyms: PRAJA1 antibody, RNF70 antibody, praja ring finger ubiquitin ligase 1 antibody, PJA1 antibody, Pja1 antibody

Background: This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants.

Alias Symbols: RNF70, PRAJA1

Protein Size: 643

Gene ID: 64219

NCBI Accession: NM_001032396, NP_001027568

UniProt: Q8NG27