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SMG6 antibody (Middle Region)
SMG6
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SMG6 Antibody
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Target
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SMG6
(Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor (SMG6))
Binding Specificity
All epitopes for SMG6 antibodies
Middle Region
Reactivity
All reactivities for SMG6 antibodies
Human
Host
All hosts for SMG6 antibodies
Rabbit
Clonality
All clonalities for SMG6 antibodies
Polyclonal
Conjugate
All conjugates for SMG6 antibodies
This SMG6 antibody is un-conjugated
Application
All applications for SMG6 antibodies
Western Blotting (WB)
Sequence
DEVSPTSWGD SRQAQASYYK FQNSDNPYYY PRTPGPASQY PYTGYNPLQY
Characteristics
This is a rabbit polyclonal antibody against EST1A. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human EST1A
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SMG6
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Target
SMG6
(Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor (SMG6))
Alternative Name
EST1A (SMG6 Products )
Synonyms
AI317223 antibody, AU041178 antibody, EST1A antibody, C17orf31 antibody, SMG-6 antibody, hSMG5/7a antibody, Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG6, nonsense mediated mRNA decay factor antibody, Smg6 antibody, SMG6 antibody
Background
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. Alias Symbols: SMG6, C17orf31, EST1A, KIAA0732, Protein Interaction Partner: UBC, SOX2, PPP1CC, gag-pol, UPF1, HBB, HDAC8, TERT, SMG5, Protein Size: 1419
Gene ID
23293
UniProt
Q86US8
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