AMER2 antibody (Middle Region)

Catalog No. ABIN5517971

Product Details anti-AMER2 Antibody

Target: AMER2 (APC Membrane Recruitment Protein 2 (AMER2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMER2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KHPEKEQQEG VPNSDEGYWD STTPGPEEDS SSSGKKAGIP RDSYSGDALY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM123A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AMER2

Target: AMER2 (APC Membrane Recruitment Protein 2 (AMER2))

Alternative Name: FAM123A (AMER2 Products)

Synonyms: 2600011E07Rik antibody, Fam123a antibody, FAM123A antibody, fam123a antibody, zgc:165647 antibody, APC membrane recruitment 2 antibody, APC membrane recruitment protein 2 antibody, Amer2 antibody, AMER2 antibody, amer2 antibody

Background: Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.

Alias Symbols: FAM123A

Protein Size: 552

Gene ID: 219287

NCBI Accession: NM_152704, NP_689917