YARS antibody (N-Term)

Catalog No. ABIN5530189

Product Details anti-YARS Antibody

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Binding Specificity: AA 160-190, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This Tyrosyl tRNA synthetase (YARS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from the N-terminal region of human Tyrosyl tRNA synthetase (YARS).

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for YARS

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Alternative Name: Tyrosyl tRNA synthetase (Yars Products)

Synonyms: CMTDIC antibody, TYRRS antibody, YRS antibody, YTS antibody, AL024047 antibody, AU018965 antibody, cb204 antibody, wu:fk52b08 antibody, YARS antibody, cmtdic antibody, tyrrs antibody, yrs antibody, yts antibody, CG4561 antibody, Dmel\\CG4561 antibody, TyrRS antibody, anon-EST:Posey261 antibody, dYARS antibody, GB10789 antibody, tyrosyl-tRNA synthetase antibody, tyrosyl-tRNA synthetase L homeolog antibody, tyrosyl-tRNA synthetase, putative antibody, tyrosine--tRNA ligase antibody, Tyrosyl-tRNA synthetase antibody, tyrosine--tRNA ligase, cytoplasmic antibody, YARS antibody, Yars antibody, yars antibody, yars.L antibody, MAL8P1.125 antibody, MEFER_RS04475 antibody, TyrRS antibody, LOC413909 antibody, LOC100163888 antibody, LOC100282315 antibody

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

Molecular Weight: 59 kDa

Gene ID: 8565

UniProt: P54577