ATP1A3 antibody (AA 805-833)

Catalog No. ABIN5530318

Product Details anti-ATP1A3 Antibody

Target: ATP1A3 (ATPase, Na+/K+ Transporting, alpha 3 Polypeptide (ATP1A3))

Binding Specificity: AA 805-833

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-833 amino acids from the Central region of human ATP1A3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ATP1A3

Target: ATP1A3 (ATPase, Na+/K+ Transporting, alpha 3 Polypeptide (ATP1A3))

Alternative Name: ATP1A3 (ATP1A3 Products)

Synonyms: AHC2 antibody, DYT12 antibody, RDP antibody, Atpa-2 antibody, Atpa1a3 antibody, ATPa1a3 antibody, atp[a]3A antibody, cb706 antibody, fj35g11 antibody, wu:fj35g11 antibody, wu:fq14g09 antibody, atp[a]3B antibody, cb705 antibody, wu:fj56a06 antibody, ATPase Na+/K+ transporting subunit alpha 3 antibody, ATPase, Na+/K+ transporting, alpha 3 polypeptide antibody, ATPase, Na+/K+ transporting, alpha 3 polypeptide L homeolog antibody, ATPase, Na+/K+ transporting, alpha 3b polypeptide antibody, ATPase, Na+/K+ transporting, alpha 3a polypeptide antibody, ATP1A3 antibody, Atp1a3 antibody, atp1a3.L antibody, atp1a3b antibody, atp1a3a antibody

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit.

Molecular Weight: 112 kDa

Gene ID: 478

UniProt: P13637

Pathways: Thyroid Hormone Synthesis, Proton Transport, Ribonucleoside Biosynthetic Process