Insulin Receptor antibody (AA 546-574)

Catalog No. ABIN5530782

The Rabbit Polyclonal anti-Insulin Receptor antibody has been validated for WB. It is suitable to detect Insulin Receptor in samples from Mouse.

Quick Overview for Insulin Receptor antibody (AA 546-574) (ABIN5530782)

Target: Insulin Receptor (INSR)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Insulin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Insulin Receptor Antibody

Binding Specificity: AA 546-574

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Insr antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 546-574 amino acids from the Central region of mouse Insr.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Insulin Receptor

Target: Insulin Receptor (INSR)

Alternative Name: Insr

Background: This receptor binds insulin and has a tyrosine-protein kinase activity. When present in a hybrid receptor with IGF1R, binds IGF1.

Molecular Weight: 156 kDa

Gene ID: 16337

UniProt: P15208

Pathways: NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity