GUCA1C antibody (C-Term)

Catalog No. ABIN5531247

Product Details anti-GUCA1C Antibody

Target: GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))

Binding Specificity: AA 171-199, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCA1C antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GUCA1C

Target: GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))

Alternative Name: GUCA1C (GUCA1C Products)

Synonyms: gcap3 antibody, GCAP3 antibody, guanylate cyclase activator 1C antibody, guca1c antibody, GUCA1C antibody

Background: GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.

Molecular Weight: 24 kDa

Gene ID: 9626

UniProt: O95843

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction