Tec Protein Tyrosine Kinase (TEC) (AA 26-55), (N-Term) antibody
Quick Overview for Tec Protein Tyrosine Kinase (TEC) (AA 26-55), (N-Term) antibody (ABIN5531707)
Target
See all Tec Protein Tyrosine Kinase (TEC) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 26-55, N-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human TEC.
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Isotype
- Ig Fraction
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Application Notes
- For WB starting dilution is: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Tec Protein Tyrosine Kinase (TEC)
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Alternative Name
- TEC
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Background
- TEC belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
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Molecular Weight
- 74 kDa
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Gene ID
- 7006
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UniProt
- P42680
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Pathways
- Fc-epsilon Receptor Signaling Pathway
Target
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