Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 511-539) antibody
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- Target See all Protocadherin gamma Subfamily C, 3 (PCDHGC3) Antibodies
- Protocadherin gamma Subfamily C, 3 (PCDHGC3)
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Binding Specificity
- AA 511-539
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PCDHGC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the Central region of human PCDHGC3.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PCDHGC3 Primary Antibody
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- Application Notes
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- Protocadherin gamma Subfamily C, 3 (PCDHGC3)
- Alternative Name
- PCDHGC3 (PCDHGC3 Products)
- Synonyms
- PC43 antibody, PCDH-GAMMA-C3 antibody, PCDH2 antibody, Pcdh2 antibody, PCDHGA11 antibody, PCDHGC5 antibody, protocadherin gamma subfamily C, 3 antibody, PCDHGC3 antibody, Pcdhgc3 antibody
- Background
- This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
- Molecular Weight
- 101 kDa
- Gene ID
- 5098
- UniProt
- Q9UN70
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