UBE4B antibody (N-Term)

Catalog No. ABIN5532321

Product Details anti-UBE4B Antibody

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Binding Specificity: AA 112-142, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This UBE4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-142 amino acids from the N-terminal region of human UBE4B.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for UBE4B

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Alternative Name: UBE4B (UBE4B Products)

Synonyms: ufd2a antibody, E4 antibody, HDNB1 antibody, UBOX3 antibody, UFD2 antibody, UFD2A antibody, 4930551I19Rik antibody, 4933406G05Rik antibody, AU014668 antibody, D4Bwg0973e antibody, UFD2a antibody, Ufd2p antibody, mKIAA0684 antibody, ubiquitination factor E4B antibody, putative ubiquitin conjugation factor E4 B antibody, ubiquitin conjugation factor E4 B antibody, ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) antibody, Ube4b antibody, LINJ_30_1070 antibody, LBRM_30_1130 antibody, Tsp_12732 antibody, Tsp_01624 antibody, ube4b antibody, UBE4B antibody

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.

Molecular Weight: 146 kDa

Gene ID: 10277

UniProt: O95155