UBE4A antibody (C-Term)

Catalog No. ABIN5532341

Product Details anti-UBE4A Antibody

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Binding Specificity: AA 1037-1067, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This UBE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1037-1067 amino acids from the C-terminal region of human UBE4A.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for UBE4A

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Alternative Name: UBE4A (UBE4A Products)

Synonyms: 4732444G18Rik antibody, 9930123J21Rik antibody, UFD2b antibody, ufd2 antibody, ubox2 antibody, E4 antibody, UBOX2 antibody, UFD2 antibody, Ab2-232 antibody, ubiquitination factor E4A S homeolog antibody, ubiquitination factor E4A antibody, ubiquitination factor E4A (UFD2 homolog, yeast) antibody, ubiquitin conjugation factor E4 A antibody, putative ubiquitination factor E4a antibody, ube4a.S antibody, Ube4a antibody, UBE4A antibody, ube4a antibody, LOC5563714 antibody, Smp_030780 antibody

Background: Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins.1 Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4.2 In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.

Molecular Weight: 123 kDa

Gene ID: 9354

UniProt: Q14139