IGSF8 antibody (AA 226-254)

Catalog No. ABIN5532597

Product Details anti-IGSF8 Antibody

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Binding Specificity: AA 226-254

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IGSF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the Central region of human IGSF8.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Alternative Name: IGSF8 (IGSF8 Products)

Synonyms: MGC77222 antibody, IGSF8 antibody, MGC151661 antibody, CD316 antibody, CD81P3 antibody, EWI-2 antibody, EWI2 antibody, KCT-4 antibody, LIR-D1 antibody, PGRL antibody, AA033172 antibody, AU041109 antibody, ESTM34 antibody, R75384 antibody, immunoglobulin superfamily, member 8 antibody, immunoglobulin superfamily member 8 antibody, igsf8 antibody, IGSF8 antibody, Igsf8 antibody

Background: IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

Molecular Weight: 65 kDa

Gene ID: 93185

UniProt: Q969P0