AKAP5 antibody (AA 115-143)

Catalog No. ABIN5532770

Product Details anti-AKAP5 Antibody

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Binding Specificity: AA 115-143

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AKAP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human AKAP5.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for AKAP5

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Alternative Name: AKAP5 (AKAP5 Products)

Synonyms: AKAP5 antibody, AKAP75 antibody, AKAP79 antibody, H21 antibody, AKAP antibody, P75 antibody, 3526401B18Rik antibody, AKAP 150 antibody, AKAP-5 antibody, AKAP150 antibody, BB098886 antibody, Gm258 antibody, P150 antibody, Akap79 antibody, A kinase (PRKA) anchor protein 5 antibody, A-kinase anchoring protein 5 antibody, AKAP5 antibody, Akap5 antibody

Target Type: Viral Protein

Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.

Molecular Weight: 47 kDa

Gene ID: 9495

UniProt: P24588

Pathways: cAMP Metabolic Process