PSG2 antibody (C-Term)

Catalog No. ABIN5533511

Product Details anti-PSG2 Antibody

Target: PSG2 (Pregnancy Specific beta 1 Glycoprotein 2 (PSG2))

Binding Specificity: AA 225-254, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSG2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-254 amino acids from the C-terminal region of human PSG2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PSG2

Target: PSG2 (Pregnancy Specific beta 1 Glycoprotein 2 (PSG2))

Alternative Name: PSG2 (PSG2 Products)

Synonyms: CEA antibody, PSBG2 antibody, PSG1 antibody, pregnancy specific beta-1-glycoprotein 2 antibody, PSG2 antibody

Background: The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).

Molecular Weight: 37 kDa

Gene ID: 5670

UniProt: P11465