ASB2 antibody (N-Term)

Catalog No. ABIN5533728

Product Details anti-ASB2 Antibody

Target: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Binding Specificity: AA 58-86, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ASB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.38 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ASB2

Target: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Alternative Name: ASB2 (ASB2 Products)

Synonyms: ASB-2 antibody, 1110008E15Rik antibody, ASB2 antibody, asb2 antibody, zgc:77223 antibody, ankyrin repeat and SOCS box containing 2 antibody, ankyrin repeat and SOCS box-containing 2 antibody, ankyrin repeat and SOCS box containing 2b antibody, ASB2 antibody, Asb2 antibody, asb2b antibody

Background: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Molecular Weight: 65 kDa

Gene ID: 51676

UniProt: Q96Q27