PRKAR1B antibody (N-Term)

Catalog No. ABIN5533848

Product Details anti-PRKAR1B Antibody

Target: PRKAR1B (Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B))

Binding Specificity: AA 55-84, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKAR1B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRKAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human PRKAR1B.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PRKAR1B

Target: PRKAR1B (Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B))

Alternative Name: PRKAR1B (PRKAR1B Products)

Synonyms: PRKAR1B antibody, AI385716 antibody, RIbeta antibody, RGD1563094 antibody, PRKAR1 antibody, zgc:153624 antibody, prkar1 antibody, protein kinase cAMP-dependent type I regulatory subunit beta antibody, protein kinase, cAMP dependent regulatory, type I beta antibody, protein kinase cAMP-dependent type 1 regulatory subunit beta antibody, protein kinase, cAMP-dependent, regulatory, type I, beta antibody, protein kinase, cAMP-dependent, regulatory subunit type I beta S homeolog antibody, PRKAR1B antibody, prkar1b antibody, Prkar1b antibody, prkar1b.S antibody

Background: Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.[supplied by OMIM].

Molecular Weight: 43 kDa

Gene ID: 5575

UniProt: P31321

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma