POLD3 antibody (C-Term)

Catalog No. ABIN5534171

This Rabbit Polyclonal antibody specifically detects POLD3 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for POLD3 antibody (C-Term) (ABIN5534171)

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLD3 Antibody

Binding Specificity: AA 416-443, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This POLD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416-443 amino acids from the C-terminal region of human POLD3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for POLD3

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Alternative Name: POLD3

Background: The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA, MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2 (MIM 600815), POLD3, and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied by OMIM].

Molecular Weight: 51 kDa

Gene ID: 10714

UniProt: Q15054

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA