DBNL antibody (C-Term)
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- Target See all DBNL Antibodies
- DBNL (Drebrin-Like (DBNL))
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Binding Specificity
- AA 292-319, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DBNL antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This DBNL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of human DBNL.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DBNL Primary Antibody
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- Application Notes
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.35 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- DBNL (Drebrin-Like (DBNL))
- Alternative Name
- DBNL (DBNL Products)
- Synonyms
- ABP1 antibody, HIP-55 antibody, HIP55 antibody, SH3P7 antibody, Abp1 antibody, mAbp1 antibody, Sh3p7 antibody, abp1 antibody, dbnl-B antibody, DBNL antibody, DKFZp459C0939 antibody, drebrin like antibody, drebrin-like antibody, drebrin like S homeolog antibody, drebrin 1 antibody, DBNL antibody, Dbnl antibody, dbnl.S antibody, LOC100148204 antibody, DBN1 antibody
- Background
- Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
- Molecular Weight
- 48 kDa
- Gene ID
- 28988
- UniProt
- Q9UJU6
- Pathways
- TCR Signaling, Regulation of Actin Filament Polymerization
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