DBNL antibody (C-Term)

Catalog No. ABIN5534210

Product Details anti-DBNL Antibody

Target: DBNL (Drebrin-Like (DBNL))

Binding Specificity: AA 292-319, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBNL antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DBNL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of human DBNL.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for DBNL

Target: DBNL (Drebrin-Like (DBNL))

Alternative Name: DBNL (DBNL Products)

Synonyms: ABP1 antibody, HIP-55 antibody, HIP55 antibody, SH3P7 antibody, Abp1 antibody, mAbp1 antibody, Sh3p7 antibody, abp1 antibody, dbnl-B antibody, DBNL antibody, DKFZp459C0939 antibody, drebrin like antibody, drebrin-like antibody, drebrin like S homeolog antibody, drebrin 1 antibody, DBNL antibody, Dbnl antibody, dbnl.S antibody, LOC100148204 antibody, DBN1 antibody

Background: Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.

Molecular Weight: 48 kDa

Gene ID: 28988

UniProt: Q9UJU6

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization