Fukutin antibody (AA 177-206)

Catalog No. ABIN5534447

Product Details anti-Fukutin Antibody

Target: Fukutin (FKTN)

Binding Specificity: AA 177-206

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fukutin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FKTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human FKTN.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Fukutin

Target: Fukutin (FKTN)

Alternative Name: FKTN (FKTN Products)

Synonyms: FCMD antibody, fcmd antibody, im:7163166 antibody, zgc:162828 antibody, FKTN antibody, CMD1X antibody, LGMD2M antibody, MDDGA4 antibody, MDDGB4 antibody, MDDGC4 antibody, D830030O17Rik antibody, Fcmd antibody, fukutin antibody, fukutin S homeolog antibody, Fukutin antibody, FKTN antibody, fktn antibody, fktn.S antibody, Bm1_09375 antibody, Bm1_09380 antibody, Bm1_44655 antibody, Fktn antibody

Background: The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 54 kDa

Gene ID: 2218

UniProt: O75072

Pathways: Regulation of Carbohydrate Metabolic Process