TESK2 antibody (AA 210-240)

Catalog No. ABIN5534739

Product Details anti-TESK2 Antibody

Target: TESK2 (Testis-Specific Kinase 2 (TESK2))

Binding Specificity: AA 210-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TESK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This TESK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human TESK2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:500

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TESK2

Target: TESK2 (Testis-Specific Kinase 2 (TESK2))

Alternative Name: TESK2 (TESK2 Products)

Synonyms: TESK2 antibody, testis-specific kinase 2 antibody, dual specificity testis-specific protein kinase 2 antibody, TESK2 antibody, LOC100548964 antibody, tesk2 antibody, Tesk2 antibody

Background: TESK2 is a dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. TESK2 phosphorylates cofilin at Ser-3. It may play an important role in spermatogenesis. This nuclear enzyme is thought to be activated by autophosphorylation on Ser-219. Expression is predominantly in testis and prostate, with highest concentrations in nongerminal Sertoli cells.

Molecular Weight: 64 kDa

Gene ID: 10420

UniProt: Q96S53

Pathways: Cell-Cell Junction Organization