U2AF1 antibody (AA 99-125)

Catalog No. ABIN5534767

Product Details anti-U2AF1 Antibody

Target: U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1))

Binding Specificity: AA 99-125

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This U2AF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This U2AF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-125 amino acids from the Central region of human U2AF1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for U2AF1

Target: U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1))

Alternative Name: U2AF1 (U2AF1 Products)

Synonyms: DDBDRAFT_0218665 antibody, DDBDRAFT_0233354 antibody, DDB_0218665 antibody, DDB_0233354 antibody, 2010107D16Rik antibody, 35kDa antibody, FP793 antibody, RN antibody, RNU2AF1 antibody, U2AF35 antibody, U2AFBP antibody, CHUNP6860 antibody, zgc:111896 antibody, U2 small nuclear RNA auxiliary factor 1 antibody, CCHC-type zinc finger-containing protein antibody, splicing factor U2AF 35 kDa subunit antibody, U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 antibody, U2 small nuclear RNA auxiliary factor 1 S homeolog antibody, U2AF1 antibody, u2af1 antibody, LOC737227 antibody, U2af1 antibody, u2af1.S antibody

Background: U2AF1 belongs to the splicing factor SR family. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers.

Molecular Weight: 28 kDa

Gene ID: 102724594, 7307

UniProt: Q01081