YWHAB antibody (N-Term)

Catalog No. ABIN5534842

Product Details anti-YWHAB Antibody

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Binding Specificity: AA 56-85, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YWHAB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This YWHAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human YWHAB.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for YWHAB

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Alternative Name: YWHAB (YWHAB Products)

Synonyms: GW128 antibody, HS1 antibody, KCIP-1 antibody, YWHAA antibody, 1300003C17Rik antibody, wu:fb22g04 antibody, wu:fr86a12 antibody, ywhab antibody, ywhab2 antibody, zgc:64092 antibody, 14-3-3beta antibody, fb80c08 antibody, fk41f08 antibody, wu:fb80c08 antibody, wu:fd11d01 antibody, wu:fk41f08 antibody, ywhab1 antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a antibody, YWHAB antibody, Ywhab antibody, ywhabb antibody, ywhab.S antibody, ywhab.L antibody, ywhaba antibody

Background: YWHAB belongs to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.

Molecular Weight: 28 kDa

Gene ID: 7529

UniProt: P31946

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location