SLC12A6 antibody (N-Term)

Catalog No. ABIN5535173

Product Details anti-SLC12A6 Antibody

Target: SLC12A6 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))

Binding Specificity: AA 13-42, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC12A6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLC12A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SLC12A6.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SLC12A6

Target: SLC12A6 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))

Alternative Name: SLC12A6 (SLC12A6 Products)

Synonyms: Kcc3 antibody, ACCPN antibody, KCC3 antibody, KCC3A antibody, KCC3B antibody, 9530023I19Rik antibody, gaxp antibody, solute carrier family 12, member 6 antibody, solute carrier family 12 member 6 antibody, Slc12a6 antibody, SLC12A6 antibody

Background: This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.

Molecular Weight: 128 kDa

Gene ID: 9990

UniProt: Q9UHW9