CHST5 antibody (C-Term)

Catalog No. ABIN5535184

Product Details anti-CHST5 Antibody

Target: CHST5 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 5 (CHST5))

Binding Specificity: AA 275-302, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CHST5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-302 amino acids from the C-terminal region of human CHST5.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CHST5

Target: CHST5 (Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 5 (CHST5))

Alternative Name: CHST5 (CHST5 Products)

Synonyms: RGD1561144 antibody, CHST5 antibody, AI173964 antibody, GST-4 antibody, Gn6st-3 antibody, I-GlcNAc-6-ST antibody, I-GlcNAc6ST antibody, glcNAc6ST-3 antibody, gn6st-3 antibody, hIGn6ST antibody, carbohydrate sulfotransferase 5 antibody, carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 antibody, Chst5 antibody, CHST5 antibody

Background: The carbohydrates of glycoconjugates are highly diverse structures with variation in monosaccharide composition, glycosidic linkage positions, and branching of chains. Further diversity is added by the covalent addition of sulfate moieties to particular hydroxyl groups and amino groups of saccharides. The sulfate modifications of glycoproteins can be extensive in amount and frequently occur at high density. They can have a profound effect on the physiochemical properties of the glycoconjugates, at least in part through the addition of negative charge. Carbohydrate sulfation plays a critical role in many biologic processes. CHST5 belongs to the GST family of sulfotransferases, which also includes CHST1 (MIM 603797), CHST2 (MIM 603798), CHST3 (MIM 603799), and LSST. These enzymes are 6-O-sulfotransferases, which add sulfate to C6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) (Lee et al., 1999 [PubMed 10491328]).

Molecular Weight: 46 kDa

Gene ID: 23563

UniProt: Q9GZS9

Pathways: Glycosaminoglycan Metabolic Process