KCNQ3 antibody (C-Term)

Catalog No. ABIN5536326

Product Details anti-KCNQ3 Antibody

Target: KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

Binding Specificity: AA 651-679, C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNQ3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KCNQ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-679 amino acids from the C-terminal region of human KCNQ3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for KCNQ3

Target: KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

Alternative Name: KCNQ3 (KCNQ3 Products)

Synonyms: KCNQ3 antibody, si:ch211-66b9.3 antibody, BFNC2 antibody, EBN2 antibody, KV7.3 antibody, potassium voltage-gated channel subfamily Q member 3 antibody, potassium voltage-gated channel, KQT-like subfamily, member 3 antibody, potassium voltage-gated channel, subfamily Q, member 3 antibody, KCNQ3 antibody, kcnq3 antibody, Kcnq3 antibody

Background: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2).

Molecular Weight: 97 kDa

Gene ID: 3786

UniProt: O43525