This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SCGB1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the Central region of human SCGB1D2.
SCGB1D2
Reactivity: Human
IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 647
Application Notes
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.46 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
SCGB1D2
(Secretoglobin, Family 1D, Member 2 (SCGB1D2))
LIPB antibody, LPHB antibody, LPNB antibody, Pbpc1bs antibody, Psbpc1 antibody, secretoglobin family 1D member 2 antibody, secretoglobin, family 1D, member 2 antibody, SCGB1D2 antibody, Scgb1d2 antibody
Background
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2.