Heparanase 2 antibody (C-Term)

Catalog No. ABIN5536544

Product Details anti-Heparanase 2 Antibody

Target: Heparanase 2 (HPSE2)

Binding Specificity: AA 451-480, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Heparanase 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HPSE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the C-terminal region of human HPSE2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Heparanase 2

Target: Heparanase 2 (HPSE2)

Alternative Name: HPSE2 (HPSE2 Products)

Synonyms: si:dkeyp-22h2.2 antibody, HPA2 antibody, HPR2 antibody, UFS antibody, UFS1 antibody, Gm968 antibody, Hpa2 antibody, heparanase 2 (inactive) antibody, inactive heparanase-2 antibody, heparanase 2 antibody, HPSE2 antibody, LOC100070602 antibody, hpse2 antibody, Hpse2 antibody

Background: Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.

Molecular Weight: 67 kDa

Gene ID: 60495

UniProt: Q8WWQ2

Pathways: Glycosaminoglycan Metabolic Process