POLG2 antibody (C-Term)

Catalog No. ABIN5537336

Product Details anti-POLG2 Antibody

Target: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Binding Specificity: AA 348-376, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This POLG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-376 amino acids from the C-terminal region of human POLG2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for POLG2

Target: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Alternative Name: POLG2 (POLG2 Products)

Synonyms: POLG2 antibody, im:7158733 antibody, si:ch211-157f15.3 antibody, HP55 antibody, MTPOLB antibody, PEOA4 antibody, POLB antibody, POLG-BETA antibody, POLGB antibody, mtpolb antibody, DNA polymerase gamma 2, accessory subunit antibody, polymerase (DNA directed), gamma 2, accessory subunit antibody, polymerase (DNA directed), gamma 2, accessory subunit L homeolog antibody, Polg2 antibody, POLG2 antibody, polg2 antibody, polg2.L antibody

Background: The accuracy of mitochondrial DNA (mtDNA) replication depends on the coordinated action of many nuclear-encoded proteins and on the correct balance of nucleotides within the mitochondrial matrix. mtDNA is replicated by DNA polymerase gamma, which is composed of a 140-kD catalytic subunit(POLG1) and a 55-kD accessory subunit (POLG2).

Molecular Weight: 55 kDa

Gene ID: 11232

UniProt: Q9UHN1