Presenilin 2 antibody (N-Term)
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- Target See all Presenilin 2 (PSEN2) Antibodies
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
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Binding Specificity
- AA 32-65, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Presenilin 2 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PSEN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from the N-terminal region of human PSEN2(Presenilin-2 NTF subunit).
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PSEN2 Primary Antibody
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- Application Notes
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For FACS starting dilution is: 1:25
For WB starting dilution is: 1:1000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
- Alternative Name
- PSEN2 (PSEN2 Products)
- Synonyms
- AD3L antibody, AD4 antibody, CMD1V antibody, PS2 antibody, STM2 antibody, ALG-3 antibody, Ad4h antibody, Alg3 antibody, PS-2 antibody, Psnl2 antibody, pre2 antibody, zf-PS2 antibody, PSNL2 antibody, PSEN2 antibody, ad4 antibody, ps2 antibody, ad3l antibody, stm2 antibody, Ps2 antibody, presenilin 2 antibody, presenilin 2 S homeolog antibody, presenilin 2 (Alzheimer disease 4) antibody, trefoil factor 1 antibody, PSEN2 antibody, Psen2 antibody, psen2 antibody, psen2.S antibody, Tff1 antibody
- Background
- Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
- Molecular Weight
- 50 kDa
- Gene ID
- 5664
- UniProt
- P49810
- Pathways
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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