RND3 antibody (AA 133-165)

Catalog No. ABIN5537459

Product Details anti-RND3 Antibody

Target: RND3 (rho Family GTPase 3 (RND3))

Binding Specificity: AA 133-165

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RND3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This ARHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the Central region of human ARHE.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for RND3

Target: RND3 (rho Family GTPase 3 (RND3))

Alternative Name: ARHE (RND3 Products)

Synonyms: ARHE antibody, Rho8 antibody, RhoE antibody, memB antibody, MGC83857 antibody, 2610017M01Rik antibody, AI661404 antibody, Arhe antibody, Rhoe antibody, RHOE antibody, arhe antibody, id:ibd2712 antibody, id:ibd2919 antibody, rho8 antibody, rnd3 antibody, wu:fc39h07 antibody, zgc:73080 antibody, wu:fd06e12 antibody, zgc:92324 antibody, Rho family GTPase 3 antibody, Rho family GTPase 3 L homeolog antibody, Rho family GTPase 3a antibody, Rho family GTPase 3b antibody, RND3 antibody, rnd3.L antibody, Rnd3 antibody, rnd3a antibody, rnd3b antibody

Background: Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925), GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855), and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).

Molecular Weight: 27 kDa

Gene ID: 390

UniProt: P61587