TRIP10 antibody (N-Term)

Catalog No. ABIN5537647

Product Details anti-TRIP10 Antibody

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Binding Specificity: AA 115-144, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP10 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRIP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the N-terminal region of human TRIP10.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TRIP10

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Alternative Name: TRIP10 (TRIP10 Products)

Synonyms: CIP4 antibody, HSTP antibody, STOT antibody, STP antibody, AI646975 antibody, Cip4 antibody, trip10 antibody, thyroid hormone receptor interactor 10 antibody, thyroid hormone receptor interactor 10a antibody, TRIP10 antibody, Trip10 antibody, trip10a antibody

Background: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Molecular Weight: 68 kDa

Gene ID: 9322

UniProt: Q15642