PAAF1 antibody (N-Term)

Catalog No. ABIN5538344

Product Details anti-PAAF1 Antibody

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Binding Specificity: AA 109-138, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PAAF1

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Alternative Name: PAAF1 (PAAF1 Products)

Synonyms: paaf antibody, rpn14 antibody, wdr71 antibody, WDR71 antibody, MGC146521 antibody, PAAF antibody, Rpn14 antibody, proteasomal ATPase associated factor 1 S homeolog antibody, proteasomal ATPase associated factor 1 antibody, paaf1.S antibody, PAAF1 antibody, paaf1 antibody, Paaf1 antibody

Background: PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.

Molecular Weight: 42 kDa

Gene ID: 80227

UniProt: Q9BRP4