MARCH11 antibody (C-Term)

Catalog No. ABIN5538625

Product Details anti-MARCH11 Antibody

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Binding Specificity: AA 308-337, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH11 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MARCH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human MARCH11.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MARCH11

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Alternative Name: MARCH11 (MARCH11 Products)

Synonyms: MARCH-XI antibody, 9630025C22 antibody, RGD1559945 antibody, membrane associated ring-CH-type finger 11 antibody, membrane-associated ring finger (C3HC4) 11 antibody, MARCH11 antibody, March11 antibody

Background: MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).

Molecular Weight: 44 kDa

Gene ID: 441061

UniProt: A6NNE9