NEIL2 antibody (N-Term)

Catalog No. ABIN5538802

Product Details anti-NEIL2 Antibody

Target: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Binding Specificity: AA 67-96, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEIL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NEIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NEIL2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NEIL2

Target: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Alternative Name: NEIL2 (NEIL2 Products)

Synonyms: NEH2 antibody, NEI2 antibody, Gm1212 antibody, nei like DNA glycosylase 2 antibody, nei like 2 (E. coli) antibody, NEIL2 antibody, Neil2 antibody

Background: NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])

Molecular Weight: 37 kDa

Gene ID: 252969

UniProt: Q969S2

Pathways: DNA Damage Repair