GEN1 antibody (N-Term)

Catalog No. ABIN5538865

Product Details anti-GEN1 Antibody

Target: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Binding Specificity: AA 60-89, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEN1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human GEN1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GEN1

Target: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Alternative Name: GEN1 (GEN1 Products)

Synonyms: 5830483C08Rik antibody, Gen antibody, RGD1559792 antibody, GEN1, Holliday junction 5' flap endonuclease antibody, GEN1 Holliday junction 5' flap endonuclease antibody, GEN1 antibody, Gen1 antibody

Background: Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Specific for 5'-overhanging flap structures in which the 5'-upstream of the flap is completely double-stranded. Prefers the blocked-flap structures similar to those occurring at replication forks, in which the 5' single-strand overhang of the flap is double-stranded (By similarity).

Molecular Weight: 103 kDa

Gene ID: 348654

UniProt: Q17RS7

Pathways: DNA Damage Repair