CHML antibody (C-Term)

Catalog No. ABIN5538883

Product Details anti-CHML Antibody

Target: CHML (Choroideremia-Like (Rab Escort Protein 2) (CHML))

Binding Specificity: AA 624-656, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHML antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CHML antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 624-656 amino acids from the C-terminal region of human CHML.

Isotype: Ig Fraction

Application Details

Application Notes: For IHC-P starting dilution is: 1:25

For FACS starting dilution is: 1:25

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CHML

Target: CHML (Choroideremia-Like (Rab Escort Protein 2) (CHML))

Alternative Name: CHML (CHML Products)

Synonyms: AI450814 antibody, E030003F13Rik antibody, REP-2 antibody, Rep2 antibody, REP2 antibody, choroideremia-like antibody, CHM like, Rab escort protein 2 antibody, Chml antibody, CHML antibody

Background: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.

Molecular Weight: 74 kDa

Gene ID: 1122

UniProt: P26374